Stable Angina Management and Treatment

Recruiting

• Conditions: Coronary Artery Disease; Stable Angina

• Registration Number: NCT03781492
• Lead Sponsor: Silesian Centre for Heart Diseases

Brief Summary

The Prospective REgistry of Stable Angina manaGEment and Treatment (PRESAGE) is an observational study on an all-comer stable angina population hospitalised in a highly specialized cardiovascular centre with cardiac surgery facilities. The aim of the study is to assess the clinical characteristics, treatment modalities, early and long-term outcomes in this population.

Detailed Description

The Prospective REgistry of Stable Angina manaGEment and Treatment (PRESAGE) is a single-center, observational study recruiting consecutive patients with stable angina, who were diagnosed and treated in the 3rd Chair and Department of Cardiology in the Silesian Centre for Heart Diseases in Zabrze, Poland. The Silesian Centre for Heart Diseases is a highly specialised cardiology centre with cardiac surgery facilities

The main objective of the PRESAGE Registry is to clarify the overall clinical characteristics of patients with stable angina, their demographics and clinical profile, current management, early and long-term outcomes, with regard to the administered treatment.

The diagnosis of stable angina was based on clinical characterization, coronary angiography, and the current guidelines of the European Society of Cardiology. Patients with vasospastic and/or microvascular angina were also included to the registry. Performance of coronary angiography is the criterion of the enrolment in the registry.

Patients with acute coronary syndromes are excluded from the analysis.

Data collection is patient-based (not event-based).

Complete patient demographics: medical history, complete hospitalization data (diagnostic and therapeutic) and in-hospital results are collected in an electronic form by the attending physician. The patients are under constant follow-up for all-cause mortality and major cardiac adverse events.

Study Timeline

• Study Start: 2006-01-01
• Study First Submitted: 2018-12-18
• Study First Submitted QC: 2018-12-18
• Study First Posted: 2018-12-20
• Status Verified: 2020-05
• Last Update Submitted: 2020-05-21
• Last Update Posted: 2020-05-26
• Primary Completion: 2026-12-31
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 25000

Inclusion Criteria

• symptom based diagnosis of stable angina

Exclusion Criteria

• acute coronary syndrome on admission
• ≤ 18 years old

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of participants with reported deaths from any cause	From date of inclusion until the date of death from any cause, assessed up to 5 year

Secondary Outcome Measures

Name	Time	Method
Number of participants with reported acute coronary syndrome driven revascularisation	From date of inclusion until the date of first event, assessed up to 5 year
Number of participants with reported myocardial infarction	From date of inclusion until the date of first event, assessed up to 5 year
Number of participants with reported cerebrovascular insult	From date of inclusion until the date of first event, assessed up to 5 year

Trial Locations

Locations (1)

3rd Chair and Department of Cardiology of Silesian Centre for Heart Diseases; 🇵🇱 Zabrze, Silesia, Poland