NCT04002817已完成不适用
Giant Cell Tumor of the Bone in Patients Under 15 Years Old: a Single Institution Case-series
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- selection and review of 50 cases of young patients with Giant Cell Tumor of bone.
研究概览
简要总结
single institution cases series review of histological and clinical data of young patient with Giant Cell Tumors
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male and female patients under 15 years old treated at Rizzoli Institute from 01 January 1982 to 31 December
- •Diagnosis of giant cell tumor of bone, aneurysmatic bone cysts with solid features and giant cell reparative granuloma.
- •Histological slides/formalin-fixed paraffin-embedded tissue tumor blocks from archive available to perform the histology analysis
- •Written informed consent prior to any study-specific analysis and/or data collection
排除标准
- •Patients with histological diagnosis different from diagnosis of giant cell tumor, aneurysmatic bone cysts with solid features, and giant cell reparative granuloma.
- •Patients with no available material for additional immunohistochemical and molecular analysis
结局指标
主要结局
selection and review of 50 cases of young patients with Giant Cell Tumor of bone.
时间窗: at baseline (Day0)
Investigators will review all the medical records, radiological imaging, and histological slides of all cases in order to collect the largest pediatric series.
次要结局
- analysis of H3F3A mutation expression on tissue tumor material(at baseline (Day0))
研究者
研究点 (1)
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