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Developmental Endothelial Locus-1, Platelet Count, and Soluble P-selectin in Overweight and Obese Subjects

Completed
Conditions
Overweight and Obesity
Registration Number
NCT05864079
Lead Sponsor
Aswan University Hospital
Brief Summary

This observational study aims to detect serum levels of Developmental Endothelial Locus-1 (DEL-1), Platelet Count, and Soluble P-selectin (sP-sel) in Overweight and Obese Subjects. The main questions it aims to answer are:

* Is there a difference in serum DEl-1 levels in overweight and obese subjects compared to normal subjects?

* Are there any relations between serum DEL-1 levels, sP-sel, and platelet count in overweight and obese subjects ?

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
66
Inclusion Criteria
  • Male patients.
  • Age (18-65) years.
  • Healthy overweight and subjects.
Exclusion Criteria
  • Patients with cardiovascular diseases.
  • Diabetic patients.
  • Previous history of thrombo-embolic diseases.
  • Patients with hyperthyroidism.
  • Patients with any type of malignancy.
  • Underlying hepatic or renal failure.
  • Major surgery within 60 days.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Serum Developmental endothelial locus-1 levels6 months

Serum developmental endothelial locus-1 in normal-weight, overweight, and obese subjects

Serum Soluble P-selectin levels6 months

Serum Soluble P-selectin in normal-weight, overweight, and obese subjects

Platelet count6 months

platelet count in venous blood samples in normal-weight, overweight, and obese subjects

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Aswan University Hospital

🇪🇬

Aswan, Egypt

Aswan University Hospital
🇪🇬Aswan, Egypt

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