NCT06053983已完成4 期
Comparison Between Atorvastatin and Rosuvastatin in Reduction of Inflammatory Biomarkers in Patients With Acute Coronary Syndrome
Rawalpindi Medical College1 个研究点 分布在 1 个国家目标入组 126 人开始时间: 2023年1月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 126
- 试验地点
- 1
- 主要终点
- Mean Change C-reactive protein
研究概览
简要总结
This study will help us to compare atorvastatin and rosuvastatin in terms of their ability to reduce biomarkers of inflammation in patients of acute coronary syndrome
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with age 18 years and above, of both genders, diagnosed with acute coronary syndrome (as per operational definition) who were not taking statins previously.
- •Patients who sign written informed consent to participate in the study.
排除标准
- •1.Patients who are taking either statins and/or any other drug which lower serum lipid levels, patients with a history of statin hypersensitivity, patients in whom statins are contraindicated.
- •2.Patients who will be surgically managed will be also excluded. 3.if coronary revascularization will be planned or anticipated at the time of screening.
- •4.Pregnant or lactating women. 5.Patients having concomitant infections which cause the rise of inflammatory markers.
研究组 & 干预措施
rosuvastatin 20 mg
Experimental
干预措施: Turbox CRP kit (Device)
rosuvastatin 20 mg
Experimental
干预措施: rosuvastatin 20 mg, (Drug)
atorvastatin 40 mg
Experimental
干预措施: Turbox CRP kit (Device)
atorvastatin 40 mg
Experimental
干预措施: atorvastatin 40 mg (Drug)
结局指标
主要结局
Mean Change C-reactive protein
时间窗: AFTER 4 WEEKS
hs -CRP (mg/l)
次要结局
未报告次要终点
研究者
Naima Shehzadi Qazi
Dr. NAIMA SHEHZADI QAZI PGT MD CARDIOLOGY
Rawalpindi Medical College
研究点 (1)
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