Postoperative Canadian Oral Anticoagulation Self-management (Post-COAGS) Trial
Not Applicable
Withdrawn
- Conditions
- Cardiovascular Abnormalities
- Registration Number
- NCT00468702
- Lead Sponsor
- Hoffmann-La Roche
- Brief Summary
This study will measure the efficacy and safety of an early postoperative anticoagulation self-management program, using the CoaguChek S device, in patients undergoing mechanical valve replacements. Patients will be randomized into a study group (self-management) or a control group (physician management).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- adult patients, 18-70 years of age;
- recipient of a mechanical heart valve (aortic and/or mitral), +/- CABG, +/- postoperative atrial fibrillation.
Exclusion Criteria
- recipient of a bioprosthetic valve;
- post-operative thrombotic events;
- pre-operative utilization of oral anticoagulation.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie anticoagulation self-management efficacy in mechanical valve patients (NCT00468702)?
How does CoaguChek S-guided self-management compare to physician-managed warfarin for postoperative valve replacement outcomes?
Which biomarkers predict successful INR control in anticoagulation self-management programs like Post-COAGS (NCT00468702)?
What adverse events are associated with early postoperative self-management using CoaguChek S in valve replacement patients?
How does Roche's CoaguChek S device compare to other point-of-care INR monitoring systems in anticoagulation management trials?