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Stress Cardiac MRI in Ischemic Patients

Conditions
Ischemic Cardiomyopathy
Registration Number
NCT04588675
Lead Sponsor
Assiut University
Brief Summary

The aim of this study is to assess the diagnostic accuracy of CMR feature-tracking (FT) at rest \& during stress with low dose dobutamine (LDD) in the evaluation of viability in ischemic cardiomyopathy (ICM) patients and compare it with delayed gadolinium enhancement (DGE).

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
50
Inclusion Criteria
  • All patients recruited into the study have chronic LV systolic dysfunction due to coronary artery disease (CAD)
Exclusion Criteria
  • All patients with a contraindication to MR study:

    • Patients with implanted non-MRI compatible electronic devices (e.g. Cardiac pacemakers, intracranial metallic clips, implanted hearing aids, etc.)
    • Patients with foreign bodies in the eye.
    • Claustrophobic patients.
  • Patients diagnosed with recent acute coronary syndrome within 4 weeks.

  • Patients who had contraindications for MRI or contrast agents, and those with poor image quality due to either inadequate breath holding or arrhythmias

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
comparison of myocardial strain with late gadolinium enhancementBaseline

analysis of the myocardial strain by low dose dobutamine and test if it can assess myocardial viability

Secondary Outcome Measures
NameTimeMethod
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