Early-stage Detection of LIver, Biliary TRAct and PancReatic Cancers
Recruiting
- Conditions
- Biliary Tract CancerLiver CancerPancreatic Cancer
- Registration Number
- NCT06139042
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Brief Summary
LIBRARY is a prospective, multi-center, observational study aimed at detecting early liver, biliary tract, and pancreatic cancers by combining assays of cell-free DNA (cfDNA) methylation, serum protein, and microRNA.
- Detailed Description
LIBRARY is a prospective, multi-center, observational study aimed at detecting early liver, biliary tract, and pancreatic cancers by combining assays of cell-free DNA (cfDNA) methylation, serum protein, and microRNA. The study will enroll approximately 458 participants diagnosed with liver, biliary tract, and pancreatic cancers, 330 individuals with corresponding benign diseases and 820 healthy participants.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1608
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The sensitivity and specificity of the cfDNA methylation model in detection of liver, biliary tract and pancreatic cancers. 24 months
- Secondary Outcome Measures
Name Time Method The sensitivity and specificity of the combined model in detection of different subtypes of cancers. 24 months The sensitivity and specificity of the combined model in detection of different stages of liver, biliary tract and pancreatic cancers. 24 months
Trial Locations
- Locations (1)
The Second Affiliated Hospital, Zhejiang University School of Medicine
🇨🇳Hangzhou, Zhejiang, China
The Second Affiliated Hospital, Zhejiang University School of Medicine🇨🇳Hangzhou, Zhejiang, ChinaWeilin Wang, M.D.Contact+8657187783820wam@zju.edu.cn