Randomized Clinical Trial for Comparison Of Intravenous Carbeitocin Versus Oxytocin In Management Of Placental Delivery In Second Trimester Interruption

Phase 4

• Conditions: CARBETOCIN FOR PREVENTION OF PLACENTAL RETAINED
• Interventions: Drug: Carbetocin; Drug: oxytocin

• Registration Number: NCT01827124
• Lead Sponsor: Wafaa Uthman Ahmed

Brief Summary

Intravenous Carbetocin is more efficient than intravenous infusion oxytocin in management of placental delivery in 2nd trimester interruption.

Detailed Description

Not available

Study Timeline

• Status Verified: 2013-04
• Study Start: 2013-04
• Study First Submitted: 2013-04-05
• Study First Submitted QC: 2013-04-08
• Study First Posted: 2013-04-09
• Last Update Submitted: 2013-10-07
• Last Update Posted: 2013-10-08
• Primary Completion: 2013-11
• Study Completion: 2013-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 140

Inclusion Criteria

• Age:16-50 years
• Pregnancy duration: 14-24weeks
• Spontaneous abortion or medical induced abortion at 14-24weeks

Exclusion Criteria

• Age less than 16years and more than 50 years
• Surgical termination
• Placenta previa
• Uterine fibroid

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
carbetocin and placebo	oxytocin	100microgram carbetocin IV and 1cc normal saline(placebo)infusion
carbetocin and placebo	Carbetocin	100microgram carbetocin IV and 1cc normal saline(placebo)infusion
oxytocin and placebo	Carbetocin	20Interntional unit oxytocin infusion and 1cc normal saline IV
oxytocin and placebo	oxytocin	20Interntional unit oxytocin infusion and 1cc normal saline IV

Primary Outcome Measures

Name	Time	Method
Record duration of spontaneous placental expulsion after delivery of fetus in second trimester interruption	at the time of delivery

Secondary Outcome Measures

Name	Time	Method
Estimation of blood loss in each group by weighing all pads put under the patient after delivery of fetus tell expulsion of placenta( before and after using of pads).	at time of delivery

Trial Locations

Locations (1)

Ain Shams university maternity hospital department of obstetrics and gynacology; 🇪🇬 Cairo, Tertiary, Egypt