NCT01227317已完成不适用
Prognostic Value of Novel Biomarkers in Patients With Shortness of Breath Attending an Emergency Department
ThermoFisher Scientific Brahms Biomarkers France1 个研究点 分布在 1 个国家目标入组 444 人开始时间: 2010年4月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 444
- 试验地点
- 1
- 主要终点
- prognostic value of PCT, MR proADM, Mr pro ANP, Copeptin and pro endothelin in SOB
研究概览
简要总结
The purpose of this study is to evaluate the capacity of some novels biomarkers Procalcitonin (PCT), Midregional Proadrenomedullin (MR pro ADM), Midregional pro-atrial natriuretic peptide (MR pro ANP), Copeptin (CT pro arginine vasopressin), Pro endothelin to stratify the risk in severe dyspnea.
详细描述
In emergency department shortness of breath (SOB)is a common symptom and its cause is not easy to be identified. The risk stratifying remains a challenge, Prognostic value of biomarkers might be helpful.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •tachypnea > 25 /min or Pa02 < 70 mmHg or SpO2 < 93%
- •diagnosis suspected: CAP, PE,EACOPD, AHF
排除标准
- •other cause of dyspnea,
- •unreachable on Day 30
结局指标
主要结局
prognostic value of PCT, MR proADM, Mr pro ANP, Copeptin and pro endothelin in SOB
时间窗: at Day 30
all cause mortality or Intensive Care Unit(ICU) admission from inclusion to Day 30
次要结局
- establish the diagnostic value of PCT and MR pro ANP(at admission)
研究者
研究点 (1)
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