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Clinical Trials/NCT04433975
NCT04433975
Completed
Not Applicable

Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes: A Randomized Controlled Trial

University of Michigan2 sites in 1 country200 target enrollmentAugust 14, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Opioid-use Disorder
Sponsor
University of Michigan
Enrollment
200
Locations
2
Primary Endpoint
Retention on Buprenorphine Treatment According to TimeLine Follow-Back - 3-months
Status
Completed
Last Updated
9 months ago

Overview

Brief Summary

The purpose of this research study is to look at the effect of programs aimed at helping people manage chronic pain and medication treatment. The program sessions focus on educational information and strategies for pain and medication management. The researchers enroll people who have chronic pain and have recently begun buprenorphine treatment to see if participants could benefit from these programs. This research study will help the researchers learn how to improve current therapies for pain and medication management.

Registry
clinicaltrials.gov
Start Date
August 14, 2020
End Date
January 19, 2025
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mark A. Ilgen

Professor of Psychiatry

University of Michigan

Eligibility Criteria

Inclusion Criteria

  • having a diagnosis of an opioid use disorders (OUD) within the past 12 months;
  • started buprenorphine (the term we use to refer to all buprenorphine products including buprenorphine/naloxone) treatment within the past 6 months
  • at least moderate or greater self-reported pain on average over the past 3 months;
  • regular and consistent access to a telephone and willingness to use the phone for study sessions.

Exclusion Criteria

  • buprenorphine medication prescribed in the form of a monthly injection and/or a transdermal patch
  • self-reported pregnancy at the time of study enrollment
  • currently living outside of the United States

Outcomes

Primary Outcomes

Retention on Buprenorphine Treatment According to TimeLine Follow-Back - 3-months

Time Frame: 3-months post enrollment

In this study, "retention on buprenorphine treatment" was defined as the time until a participant stopped taking their medication for 7 or more days in a row. This information was collected using a calendar recall method, the TimeLine Follow-Back (TLFB) measure at 3 months. The average number of days participants remained on buprenorphine before this happened was calculated, using the data collected at 3-month follow-up.

Secondary Outcomes

  • Retention on Buprenorphine Treatment According to TimeLine Follow-Back - 12 Months(12-months post enrollment)
  • Average Change in Self-reported Level of Pain Intensity on the Numerical Rating Scale for Pain Intensity (NRS-I) at 3-month Follow up (Compared to Baseline)(3-months post enrollment)
  • Average Change in Self-Reported Level of Pain Related Functioning on the Brief Pain Inventory - Short Form (BPI) at 3-month Follow up (Compared to Baseline)(3-months post enrollment)
  • Percent Days Abstinent From Substance Use on the TimeLine Follow-Back - 3-months(3-months post enrollment)
  • Average Change in Self-reported Level of Pain Intensity on the Numerical Rating Scale for Pain Intensity (NRS-I) at 12-month Follow up (Compared to Baseline)(12-months post enrollment)
  • Average Change in Self-Reported Level of Pain Related Functioning on the Brief Pain Inventory - Short Form (BPI) at 12-month Follow up (Compared to Baseline)(12-months post enrollment)
  • Percent Days Abstinent From Substance Use on the TimeLine Follow-Back - 12 Months(12-months post enrollment)

Study Sites (2)

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