Effect of D-Ribose L-Cysteine (RiboCeine) on oxidative stress markers and glutathione levels in healthy individuals
Not Applicable
- Conditions
- AntioxidantM01.774.500
- Registration Number
- RBR-84vqcn6
- Lead Sponsor
- niversidade do Sul de Santa Catarina
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Healthy individuals; of both sexes; between the ages of 40 and 59 years
Exclusion Criteria
Individuals who use supplements to increase mitochondrial activity; nitric oxide; antioxidants or to reduce inflammation; and who have injuries that may make participation in the study difficult
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method It is expected that individuals who will receive supplementation with Ribose Cysteine will show a significant decrease in the oxidative stress marker (malondialdehyde) and an increase in the antioxidant enzyme (glutathione)
- Secondary Outcome Measures
Name Time Method It is expected that individuals supplemented with Cysteine Ribose have demonstrated improvement in the Oxidative Stress Assessment tool, identifying themselves with fewer stressors;The effects of Cysteine Ribose in healthy individuals will be evaluated, on serum levels of: Citrate synthase; Malondialdehyde (MDA); Total glutathione levels; High sensitivity C-reactive protein (hs-CRP)<br>;It is expected that individuals supplemented with Ribose Cysteine will have lower scores obtained on the Fatigue Assessment Scale than the scores prior to the start of treatment;It is expected that individuals supplemented with Ribose Cysteine will have a lower score on the Perceived Stress Scale than the scores prior to the start of treatment;It is expected that individuals supplemented with Cysteine Ribose will have better sleep quality reported through the Pittsburgh Quality of Sleep Index (PSQI-BR) tool, showing a reduction in the score after supplementation