microRNA Profile in Umbilical Cord Blood NK Cells

• Conditions: Pregnant Women
• Interventions: Other: blood donation

• Registration Number: NCT00751569
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Umbilical cords contain immature blood cells, including a group of lymphocytes, that are important in the so-called natural immunity. We want to study the cytokine levels in umbilical cord NK cells and its regulation a family of newly identified small RNAs (microRNAs).

Detailed Description

Our preliminary data pointed to the possibility of cytokine regulation by microRNAs in NK lymphoma and NK lymphoma cell lines. We want to use umbilical cord blood as controls for the biological significance in normal NK cell development.

Study Timeline

• Status Verified: 2008-09
• Study Start: 2008-09
• Study First Submitted: 2008-09-10
• Study First Submitted QC: 2008-09-11
• Last Update Submitted: 2008-09-11
• Study First Posted: 2008-09-12
• Last Update Posted: 2008-09-12
• Study Completion: 2009-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 5

Inclusion Criteria

• Normal pregnant women

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Exclusion Criteria

• None

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
A1	blood donation	A group of 3 to 5 pregnant women as donors for umbilical cord blood

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan