Peripherally Inserted Central Venous Catheter Insertion Site and Complication Rates in Neonates
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Catheterization, Peripheral
- Sponsor
- University of Calgary
- Enrollment
- 320
- Locations
- 1
- Primary Endpoint
- Primary outcome is the presence of any complication which necessitates PICC removal
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
This study examines whether there is an association between the PICC insertion site and the complications necessitating PICC removal in neonates admitted to neonatal intensive care unit.
Investigators
Amuchou Soraisham
Neonatologist
University of Calgary
Eligibility Criteria
Inclusion Criteria
- •Neonates of all gestational ages admitted to Foothills Medical Centre and Alberta Children's Hospital Neonatal Intensive Care Unit (NICU)
- •Peripherally inserted central venous catheter (PICC) line insertion planned as part of NICU care
- •Venous access available in both upper(above umbilicus) and lower body
Exclusion Criteria
- •Local infection at potential site of insertion
- •Hemangioma, lymphangioma or malformations in the region of insertion
- •Major chromosomal anomalies
Outcomes
Primary Outcomes
Primary outcome is the presence of any complication which necessitates PICC removal
Time Frame: Through study completion, within 4 weeks
Line infiltration will be defined as extravasation of fluid into soft tissue around the region of the catheter tip. Line occlusion will be defined as inability to infuse fluid, resulting in removal of line. Phlebitis will be defined as presence of a linear red streak developing along the superficial veins from the catheter insertion site. Line associated thrombosis will be defined as ultrasound proven evidence of an occlusive thrombus in an anatomic location in proximity to the site of PICC.CLABSI will be defined according to Center for Disease Control definitions 26, that is, (1) confirmed primary bloodstream infection with (2) one of following clinical signs of infection (fever, hypothermia, apnea, or bradycardia) and (3) presence of central catheter at the time of or within 48 hours before the onset of the infection. Major life-threatening complications will include pleural effusion, pericardial effusion and cardiac tamponade, retroperitoneal extravasation.
Secondary Outcomes
- Secondary outcome will be time to complication post insertion(Through study completion, within 4 weeks)