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Clinical Trials/NCT04182217
NCT04182217
Completed
N/A

Descriptive and Correlational Study of the Epidemiological, Clinical and Etiological Characteristics of Peritonitis in the Surgical Department of the State University Hospital of Haiti During the Period From January 2013 to December 2018

Universite d'Etat d'Haiti1 site in 1 country91 target enrollmentSeptember 10, 2018
ConditionsPeritonitis

Overview

Phase
N/A
Intervention
Not specified
Conditions
Peritonitis
Sponsor
Universite d'Etat d'Haiti
Enrollment
91
Locations
1
Primary Endpoint
Temperature
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The primary objective:

To study the prevalence, etiology, and factors associated with the severity of peritonitis and its complications in the surgery department of the State University Hospital of Haiti.

Secondary objectives:

  • Identify epidemiological characteristics.
  • Describe the main etiologies encountered in the service
  • Measure the time required for treatment and its consequences on the evolution of peritonitis.

Detailed Description

Generalized secondary peritonitis is one of the most common emergencies encountered in surgical departments . It is a major surgical condition with a mortality of up to 20% and classified as the third most common cause of surgical abdomens after appendicitis and intestinal obstruction . Delays in surgical management are conditions that increase mortality. While early prognostic assessment of peritonitis is essential for the objective classification of the severity of the disease, the late presentation of the majority of patients to health facilities affects this situation, further complicating effective management and promoting the occurrence of complications . It has been observed that classifying the severity of peritonitis has a major contribution to decision-making and improves management. Thus, many scoring systems have been designed and successfully used to assess the severity of acute peritonitis, including: Acute physiology and chronic health evaluation (APACHE) II score, Simplified acute physiology score (SAPS), Sepsis severity score (SSS), Ranson score, Imrite score, Mannheim peritonitis index (MPI) 6. The Mannheim Peritonitis Index (MPI) is a specific score, which is highly accurate and allows clinical parameters to be easily manipulated, allowing the individual prognosis of patients with peritonitis to be predicted . In Haiti, few studies on surgical pathologies are available. And with regard to peritonitis, only two thesis works have been listed on the subject, including one carried out at the Justinian University Hospital of Cap-Haitian on 176 patients by Dr. Jacques Julmice, who presents the main etiologies of peritonitis over a 5-year period. And the other one carried out at the Albert Schweizer Hospital by Dr. Moise Aristide, still on the etiological factors of peritonitis. These two studies are carried out outside the country's metropolitan region (the most populated region) and that they only explored the different etiologies without taking into account the time required for treatment and the gravity factors of peritonitis. Therefore, our study aims to explore the demographic, clinical and etiological factors of peritonitis in the main referral hospital in the metropolitan region of the country, as well as the time required for treatment and its relationship with the severity of the disease.

Registry
clinicaltrials.gov
Start Date
September 10, 2018
End Date
October 1, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Universite d'Etat d'Haiti
Responsible Party
Principal Investigator
Principal Investigator

JEAN PAUL Axler

Medical Student

Universite d'Etat d'Haiti

Eligibility Criteria

Inclusion Criteria

  • Patients whose peritonitis diagnosis was made and operated on in the department during the period.
  • Patient whose record is identified (with age, sex) with at least the clinical and etiological diagnosis identified in the operating protocol.

Exclusion Criteria

  • Patients with incomplete records.
  • Cases of post-operative peritonitis.
  • Patient under 10 years of age

Outcomes

Primary Outcomes

Temperature

Time Frame: immediately after admission, up to 30 minutes

Temperature in celsius reported in the file of entry

Etiological Diagnosis

Time Frame: immediately post-surgery

final diagnosis retained in the operating protocol

Heart Rate

Time Frame: immediately after admission, up to 30 minutes

Heart rate number of beats/min reported in the file entry for each patients

Respiratory Rate

Time Frame: immediately after admission, up to 30 minutes

Respiratory rate number of cycle/min reported in the file of entry

Blood Pressure

Time Frame: immediately after admission, up to 30 minutes

Systolic Blood pressure in mmHg reported in the file of entry

Demographic Parameters

Time Frame: during admission

Age in years described in the admission file

Secondary Outcomes

  • Onset of Symptoms(immediately after admission)
  • Delay in Pre-op(immediately post-surgery)
  • Delay in Hospital(immediately after hospitalization)
  • Delay in Post-op(immediately after hospitalization)

Study Sites (1)

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