Body Responses to Bean Physical Form and "Beano"

Not Applicable

Completed

• Conditions: Appetite and Glucose Responses
• Interventions: Other: blended lentils; Other: whole lentils; Other: no lentils

• Registration Number: NCT02110511
• Lead Sponsor: Purdue University

Brief Summary

The aim of this study is to determine the effects of bean physical form (whole versus blended) and Beano on postprandial responses. The postprandial responses the investigators will examine include blood glucose, appetite, metabolic rate, physical symptoms, and mood. To accomplish this aim the investigators will conduct a randomized, placebo-controlled trial in overweight and obese but otherwise healthy (non-diabetic) men and women

Detailed Description

Not available

Study Timeline

• Study Start: 2011-08
• Primary Completion: 2012-10
• Study Completion: 2012-10
• Status Verified: 2014-04
• Study First Submitted: 2014-04-08
• Study First Submitted QC: 2014-04-09
• Last Update Submitted: 2014-04-09
• Study First Posted: 2014-04-10
• Last Update Posted: 2014-04-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Aged 18-55 years old
• Body mass index (BMI) 18.5-40 kg/m2
• Generally healthy
• A non-smoker
• Any ethnicity
• Free of chronic diseases and not taking medications or dietary supplements known to affect energy regulation or appetite

Exclusion Criteria

• Beano drug label warnings including galactosemia, severe liver or kidney disease, allergies or sensitivities to any of the ingredients in Beano
• Peri and postmenopausal women
• Pregnant or lactating women (currently and within the past 1 year)
• Currently dieting or consuming unusual or a medically prescribed diet
• Net weight loss or gain (>5 lbs) within the last six months
• Consuming 1/2c per day or more of legumes, not including peanuts
• Having taken Beano any time in the past 3 months
• Extreme problems digesting beans
• Fasting glucose >126 mg/dl
• Blood pressure >140/90 mmHg
• Moderate intensity or higher intensity exercise > 6 h/wk
• Predicted energy requirement < 2000 kcal/d or >4000 kcal/d

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
alpha-gal & blended lentils	blended lentils	3 capsules of alpha-gal taken with blended lentils
alpha-gal & whole lentils	whole lentils	3 calpsules of alpha-gal taken with whole lentils
alpha-gal & no lentils	no lentils	3 capsules of alpha-gal taken with no lentils control
Placebo & blended lentils	blended lentils	3 capsules of placebo taken with blended lentils
Placebo & whole lentils	whole lentils	3 capsules of placebo taken with whole lentils
Placebo & no lentils	no lentils	3 capsules of placebo taken with no lentils control

Primary Outcome Measures

Name	Time	Method
Appetite	3 hours	Subjects were given an appetite questionnaire to complete at time 0, 20, 40, 60, 120 and 180

Secondary Outcome Measures

Name	Time	Method
Blood glucose	3 hours	Finger prick blood were taken at time 0, 20, 40, 60, 120 and 180 for glucose measurement using a glucometer
fasting and postprandial energy expentidure	4 hours	Fasting energy expenditure was measured for thirty minutes before meal and beano intervensions were given and at postprandial time points 20, 40, 60, 120 and 180, postprandial energy expenditure was measured for 15 minutes at each time point
gastrointestinal symptoms	3 hours	At timepoints 0, 20, 40, 60, 120 and 180, gastroinstinal symptoms were assessed using a questionnaire

Trial Locations

Locations (1)

Purdue University; 🇺🇸 West Lafayette, Indiana, United States