Ingrained health

Not Applicable

Completed

• Conditions: Cardiovascular health; Circulatory System

• Registration Number: ISRCTN77566972
• Lead Sponsor: Cereal Partners Worldwide (Switzerland)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-08-13
• Study Completion: 2015-06-01
• Last Update Posted: 24 August 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 82

Inclusion Criteria

1. Aged 40-70 years
2. Generally healthy subjects, as determined by clinical examination and medical history
3. BMI between 25 and 35 kg/m2
4. Slightly elevated blood pressure after 5 minutes supine position (systolic blood pressure >120mmHg)
5. Mildly elevated plasma cholesterol (> 5.5mM)
6. Non smoking

Exclusion Criteria

1. Known allergy to study (wheatbased) foods
2. History of metabolic disease (i.e.diabetes, cardiovascular disease) relevant for drug treatment
3. Chronic renal insufficiency
4. Local or general treatment (i.e. prescription medications, overthecounter medications, dietary supplements or herbal supplements) known to interfere with the evaluation of the studied parameters
5. Subject having had a general anaesthesia in the month preceding inclusion, or gastrointestinal surgery
6. Pregnant or breastfeeding subject
7. Use of laxatives
8. Known allergies to cereals
9. Dislike of provided study foods

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Resting blood pressure, measured at screening visit and 0, 4, 6, 8, 12, 14, 16 weeks<br> 2. 24 hour blood pressure, measured at screening visit and 0, 4, 8, 12, 16 weeks<br> 3. Lipid profile, measured at screening visit and 0, 4, 8, 12, 16 weeks<br>