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earn2Walk (Brain meets spine: the neural origin of toddler*s first step) PART II - Children with cerebral palsy

Completed
Conditions
Cerebral palsy
spastic paresis
10028037
Registration Number
NL-OMON49385
Lead Sponsor
Vrije Universiteit
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
80
Inclusion Criteria

Infants aged 1 month to 3 years (corrected age);
Neurological dysfunction suggestive of development of cerebral palsy;
Cystic periventricular leukomalacia;
Uni/Bilateral parenchymal lesion of the brain;
Other structural damage of the brain.

Exclusion Criteria

Functional surgery on bones and/or muscles of the legs or selective dorsal
rhizotomy in the last 12 months;
Severe epilepsy.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The primary study parameters will be the number of locomotor primitives<br /><br>(derived from EMG measurements), the topological changes of brain functional<br /><br>networks (derived from EEG measurements), and cortico-muscular coherence<br /><br>(derived from EMG and EEG).</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>The secondary study parameters are kinematics and kinetics.</p><br>
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