To evaluate the dose requirement of epidural levobupivacaine with fentanyl for adequate pain relief in labour after combined spinal epidural analgesia
Phase 4
- Conditions
- Health Condition 1: null- Primigravida full term (37-40weeks) in active labour with ASA I and II
- Registration Number
- CTRI/2017/09/009624
- Lead Sponsor
- Dr L H Hiranadani Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA I & II Primigravida with singleton full term pregnancy with vertex presentation.
2. Patients giving valid consent.
3. Patients in active stage of induced labour with cervical dilatation of 3 to 5cms.
Exclusion Criteria
1. Patient refusal
2. ASA grade more than II.
3. Gestational age less than 37 weeks or with malpresentation/ multiple gestation.
4. Patients with PIH /Eclampsia.
5. Pateints who have received IV/IM opiods within 4hrs of epidural insertion.
6. Entered in second stage of labour.
7. Delivery within 30mins of intrathecal analgesia.
8. Patients with contraindication to regional analgesia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the total epidural dose requirement for labour analgesia in patients given intrathecal fentanyl with and without levobupivacaine for labour analgesiaTimepoint: After delivery of the baby and end of second stage of labour
- Secondary Outcome Measures
Name Time Method 1. Time taken to achieve VAS 0. <br/ ><br>2. Total duration of analgesia post intrathecal injection. <br/ ><br>3. Level of sensory blockage. <br/ ><br>4. Incidence of motor blockage. <br/ ><br>5. Perception of uterine contractions. <br/ ><br>6. Haemodynamic parameters <br/ ><br>7. Duration of labour and neonatal outcome. <br/ ><br>8. Side effects: nausea and vomiting <br/ ><br> pruritis <br/ ><br> incidence of fetal bradycardia urinary retentionTimepoint: At the begining of labour and during labour and at the end of labour.