Effect of Subcostal Transversus Abdominis Plane Block on Early Postoperative Pain in Laparoscopic Cholecystectomy: Randomized, Controlled Trial
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Numerical Rating Scale (NRS) 15 min after entering recovery room
Study Overview
Brief Summary
Transversus abdominis plane (TAP) block has gained popularity for the control of postoperative pain in various surgeries. Three studies showed inconsistent result on pain control after TAP block in laparoscopic cholecystectomy. The TAP technique used in these studies was classic ultrasound guided TAP block. Besides periumbilical incision, sub-xiphoid incision is usually made during laparoscopic cholecystectomy. As typical posterior TAP rarely extend above T8, the investigators undergo subcostal TAP block for this type of surgery. The investigators are going to investigate the effect of subcostal TAP on early postoperative pain after laparoscopic cholecystectomy.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 20 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age 20-65 patients scheduled elective laparoscopic cholecystectomy
Exclusion Criteria
- •Patient refusal
- •Allergy to ropivacaine
- •Coagulopathy
- •Morbid obesity (BMI>35 kg/m2)
- •Previous abdominal surgery.
Arms & Interventions
Control
Control group receiving saline instead of ropivacaine
Intervention: Placebo Ultrasound guided subcostal TAP block (Procedure)
TAP
TAP group receiving ropivacaine total of 150 mg at TAP under US
Intervention: Ultrasound guided subcostal TAP block (Procedure)
Outcomes
Primary Outcomes
Numerical Rating Scale (NRS) 15 min after entering recovery room
Time Frame: 15 min after entering recovery room
Secondary Outcomes
- NRS at 4h, 24h, and 48 h after surgery(4h, 24h, and 48 h after surgery)
- Fentanyl consumption at recovery room(Up to 3 hours until discharge from recovery room)
- Recovery room stay(Up to 3 hours from entering recovery room to discharge)
- Incidence of postoperative nausea and vomiting (PONV)(Up to 3 hours during recovery room stay)
Investigators
Kim Sang-Hyun
Associate professor
Soonchunhyang University Hospital