MedPath

Effect of alogliptin/pioglitazone on endothelial function and Visceral fat of Type 2Diabetes

Not Applicable
Completed
Conditions
Type2 diabetes
Registration Number
JPRN-UMIN000023463
Lead Sponsor
Dokkyo medical university hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients with hypersensitivity to the components of alogliptin or sulfonylurea. 2)Patients with severe ketosis ,diabetic coma or pre coma. 3)Patients with severe infection,before and after surgery,severe trauma. 4)Patient with advanced renal dysfunction(eGFR<30) or patient on dialysis. 5)Patients with severe liver dysfunction. 6)Patients with pregnancy or possibility. 7)Patients whom physician in charge considered inappropriate for study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Endothelial function after 6 months on pioglitazone or sulfonylurea
Secondary Outcome Measures
NameTimeMethod
The change of body weight,blood pressure,visceral fat HbA1c,blood glucose,LDL,HDL,non HDL,adiponectin,and 8epiPGF2A after 6 months treatment of pioglitazone or sulfonylurea
© Copyright 2025. All Rights Reserved by MedPath