Think FAST Research Study

Not Applicable

Completed

• Conditions: Age-related Cognitive Decline
• Interventions: Other: PNF

• Registration Number: NCT04938778
• Lead Sponsor: Arizona State University

Brief Summary

To test a 14-hour prolonged nightly fasting (PNF) protocol in a group of older adults (≥ 65 years old) with self-identified age-related cognitive decline (ARCD) on the primary outcome of neurocognitive function and performance as measured by objective outcomes. The investigators will use an 8-week single group pre-post pilot study design to measure outcomes related to neurocognitive function and performance and cardiometabolic risk factors (i.e., sleep disturbances, body mass index).

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-01
• Study First Submitted: 2021-03-10
• Study First Submitted QC: 2021-06-16
• Study First Posted: 2021-06-24
• Primary Completion: 2022-07-30
• Study Completion: 2022-07-30
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-03
• Last Update Posted: 2022-08-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• 65 or older
• Self-identified age-related cognitive decline (ARCD)
• Has a text capable phone and access to wifi

Exclusion Criteria

• Diagnosed with an eating disorder in the past 20 years
• Works a night shift
• Cannot participate in a 14 hour fast
• Has diabetes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Intervention Arm	PNF	8 week 14 hour prolonged nightly fasting intervention.

Primary Outcome Measures

Name	Time	Method
Memory and Attention Phone Screener (MAPS)	8 weeks	Cognitive Function and Performance Test.

Secondary Outcome Measures

Name	Time	Method
Creature of Habit Scale (COHS)	8 weeks	Scale to asses routine habits. Each item has a minimum of zero and a maximum of 4 where 4 means a more habitual nature.
Salivary Cortisol	8 weeks	Measure of cortisol via participant saliva samples.
Mindful Eating Scale (MES)	8 weeks	Scale to asses behaviors related to mindful eating. Each item has a minimum of zero and a maximum of 4 where 4 means less eating awareness.
Body Mass Index (BMI)	8 weeks	Self-reported body measurements .
Insomnia Severity Index (ISI)	8 weeks	Scale to asses insomnia symptoms. The scale has a minimum of zero and maximum of 28 where zero would be absence of insomnia and 28 would be severe insomnia.
Rapid Eating Assessment for Participants Scale (REAPS)	8 weeks	Scale to asses eating behaviors. The scale has a minimum of 13 and a maximum of 39. Higher scores indicate higher diet quality.

Trial Locations

Locations (1)

Arizona State University; 🇺🇸 Phoenix, Arizona, United States