NCT05807672招募中不适用
MARF-E- Magnetic Resonance Fingerprinting in the Imaging of Endometrial Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2022年4月23日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Association between T1-, T2- and diffusion-mappings and risk group classification
研究概览
简要总结
In this context, the aim of this study is to investigate the role of MRF in endometrial cancer. Several applications are possible. Firstly, T1-, T2- and DWI-mappings can be associated to molecular risk group classification, in order to stratify patients' risk without recurring to surgery. MRF parameters can be also correlated to prognosis, both in terms of disease-free survival (DFS) and overall survival (OS).
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients with biopsy-proven endometrial cancer;
- •Women aged > 18 years old;
- •Signed Informed consent.
排除标准
- •Previous history of neoplasm;
- •Concurrent malignancies at other sites.
结局指标
主要结局
Association between T1-, T2- and diffusion-mappings and risk group classification
时间窗: 3 months
次要结局
- Correlation between T1-, T2- and diffusion mappings and DFS and OS(3 years)
- Diagnostic accuracy of T1-,T2- and diffusion-mappings deriving from MRF in myometrial invasion detection(3 months)
- Evaluation of Radiomic and Radiogenomic models to predict recurrence in early stage EC and to predict DFS and OS(3 years)
- Diagnostic accuracy of T1-,T2- and diffusion-mappings and pathological nodal involvement(3 months)
研究者
研究点 (1)
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