Effect of curcumin versus placebo on the improvement of sever traumatic brain injury

Phase 3

Recruiting

• Conditions: Head injury.; Crushing injury of head

• Registration Number: IRCT20120215009014N305
• Lead Sponsor: Hamedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 168

Inclusion Criteria

Age of 18 to 70 years,
Head trauma with past 24 hours,
Conscious level of 8 or less,
Candidate for craniotomy surgery

Exclusion Criteria

Pregnancy or breastfeeding,
Low blood pressure,
Absence of brain reflex,
Renal failure

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Consciousness level. Timepoint: Daily for three weeks. Method of measurement: Using the Glasgow Coma Score (GCS).;Improvement of neurological defect. Timepoint: 3 and 6 months after the intervention. Method of measurement: With clinical examination.;Nervous system function. Timepoint: 3 and 6 months after the intervention. Method of measurement: Based on the Glasgow Outcome Score (GOS).;Brain edema. Timepoint: 3 weeks after the intervention. Method of measurement: Using CT scan.