The effects of a single administration of a moderate dose of caffeine on cognitive control and spontaneous EEG theta/beta ratio

Completed

• Conditions: Not relevant; Gezonde studenten

• Registration Number: NL-OMON42339
• Lead Sponsor: niversiteit Leiden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

- Female
- Age 18-25 years
- Consuming less than 100mg of caffeine (about one cup of coffee) per day on average
- Fluent in Dutch language

Exclusion Criteria

- Severe physical or psychological morbidity that would adversely affect participation
- Habitual smoking
- Use of psychopharmaceutics

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>a) The change in performance (as measured with reaction times; RTs) on two<br /><br>cognitive tasks (n-back task & switch task) after caffeine consumption,<br /><br>relative to placebo consumption. We expect performance to improve (RTs to<br /><br>decrease) after caffeine consumption.<br /><br>b) The change in the ratio between EEG measured theta and beta oscillations<br /><br>after caffeine consumption (relative to placebo consumption). We expect<br /><br>theta/beta ratio to decrease after caffeine consumption, thereby mediating the<br /><br>effects of caffeine on cognitive performance.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>a) The moderating effects of baseline dopamine activity (measured with baseline<br /><br>spontaneous eye blink rates and theta/beta ratio) on the effects of caffeine on<br /><br>cognition.<br /><br>b) The possible confounding effects of self-reported ADHD symptoms, sleepiness,<br /><br>and anxiety on the effects of caffeine on cognition.</p><br>