Does 12 weeks of eating a habitual diet including almonds, compared with a habitual nut-free diet, affect cognitive performance and cardiometabolic health in healthy overweight adults?

Assoc.Prof Alison Coates0 个研究点目标入组 150 人开始时间: 2015年11月27日最近更新: 2020年1月13日

试验速览

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•Overweight healthy adults with BMI between 25-39.9 kg/m2. Non-smokers.
•Weight stable in the past 3 months. No diagnosis of cognitive impairment or memory loss or a Montreal Cognitive Assessment (MoCA) score of >18. Non-restrained eaters. No allergies or food intolerances to nuts or ingredients in control foods.

•Have a BP of > 160/100 mmHg. Regularly consume large amounts of nuts or nut butters (more than 210 g per week). Have cardiovascular disease (including uncontrolled high blood pressure) and chronic diseases including Type 1 and 2 diabetes. Has a history of depression in the prior 2 years or Geriatric Depression Score (GDS)-15 score of more than 10. Has any neurological disorder, including but not limited to, Alzheimer’s disease, Parkinson’s disease, stroke, intracranial haemorrhage and brain lesions including tumours. Has a recent history (within 12 months) or strong potential for alcohol abuse. Defined as >14 standard drinks per week. Are colour blind. Have changed medications in the last 3 months. Take medications or supplements that may have an impact on the study outcomes. Have a history of infective or inflammatory brain disease or head injury. Are planning on dieting to control weight during the study. Are already involved in a research study that may influence the outcomes of this study within 30 days of commencing present study. Are pregnant or breast feeding.

发起方

Assoc.Prof Alison Coates