Mannitol to prevent an exacerbation of Complex Regional Pain Syndrome (CRPS) after hand surgery.

Completed

• Conditions: Complex Regional Pain Syndrome

• Registration Number: NL-OMON25885
• Lead Sponsor: none

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

1. Age at least 18 jaar;

2. History of CRPS, indicated by the presence of the following characteristics during the past 3 years (adapted CRPS I criteria according to Bruehl)

Exclusion Criteria

1. Allergy to mannitol;

2. Allergy to hydrochlorothiazide;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The Impairment Level Sum Score (ISS) after 3 months, which is a composite score, accounting for pain, edema, temperature and range of motion.

Secondary Outcome Measures

Name	Time	Method
1. Disability of Arm, Shoulder and Hand, Dutch Language Version (DASH-DLV) score;<br /><br>2. Individual components of ISS;<br /><br>3. Perioperative VAS-pain scores;<br /><br>4. Number of medication changes;<br /><br>5. Side effects.