Improvement of diagnosis of major depressive and bipolar disorder: an fMRI-study.
Recruiting
- Conditions
- major depressive disorderbipolar disorderdiagnosisfMRI
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1. Major depressive disorder (MDD) and Bipolar I and Bipolar II (BD I and BD II) patiens of both sexes;
2. Age 18-60 years;
Exclusion Criteria
MDD and BD I and BD II patients:
1. Electroconvulsive therapy within two months before scanning;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We will compare performance on the neuropsychological task between MDD, BD I and HC, measured by reponse time, number of omissions and number of errors. The same outcomes will be examined fot the neuroimaging tasks. We will compare brain responses of fMRI tasks relative to control conditions between MDD, BD and HC. We will compare responses in predefined ventral and dorsal brain regions (dorsolateral prefrontal cortex (PFC), ventral PFC, orbitofrontal, limbic and subcortical regions).
- Secondary Outcome Measures
Name Time Method