Evaluation of vector control tools for dengue outbreak response
Completed
- Conditions
- Dengue, severe dengueInfections and InfestationsDengue fever [classical dengue]
- Registration Number
- ISRCTN75270383
- Lead Sponsor
- iverpool School of Tropical Medicine (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 2500
Inclusion Criteria
All occupied households
Exclusion Criteria
1. Business-only premises
2. Unoccupied premises
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficacy of the intervention will be determined by measuring a range of entomological indices. <br><br>Acceptance and other perceptions of the interventions will be evaluated using brief questionnaire surveys at baseline and final follow-up.<br>1. Measure the impact of each treatment on the adult and larval mosquito population densities in the clusters. Dengue vector populations will be measured using the Adult index (AI - proportion of houses positive for adult Ae. aegypti) and standard Stegomyia indices: <br>1.1. Breteau index (BI - number of containers with immature vector stages/100 houses), House index (HI - percentage of houses found with immature stages of Ae. aegypti) and container index (CI - percentage of water-holding containers found with immature stages of Ae. aegypti). We will also measure the Pupal index (PI - number of pupae per number of people), a proxy for adult populations, and deploy ovitraps as sensitive indicators of Aedes spp. presence or absence.
- Secondary Outcome Measures
Name Time Method Interview surveys used to determine: <br>1. Household characteristics <br>2. Precious and current vector control intervention <br>3. Understanding of the local population's knowledge, attitudes and practice about dengue prevention and control, and the interventions being tested <br>4. Insecticide-susceptibility assays undertaken before, at follow-up surveys and after intervention<br><br>Each house will be geo referenced with a handheld global positioning system receiver to permit potential effects between clusters to be quantified.