Reducing non-steroidal anti-inflammatory drug use in people with knee osteoarthritis

Not Applicable

Recruiting

• Conditions: knee osteoarthritis; Musculoskeletal - Osteoarthritis; Physical Medicine / Rehabilitation - Physiotherapy

• Registration Number: ACTRN12619000363189
• Lead Sponsor: niversity of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-07
• Last Update Posted: 10 December 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Aged 45 years or older
- Activity-related joint pain
- Morning stiffness lasting <30 minutes
- Report regular use of non-steroidal anti-inflammatory drugs of any class (the participants must have used them on average of 5 or more days in the previous 4 weeks before the commencement of the trial)
- Have access to the Internet

Exclusion Criteria

- Chronic systemic inflammatory conditions
- Neurological condition affecting a participant’s ability to ambulate
- Unstable cardiovascular condition
- Regular use of strong opioids (e.g. morphine)
- Participants must not be involved in any active therapy for their knee osteoarthritis such as a structured exercise program, designed by a physiotherapist but they can be involved in their own leisurely physical activity

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
recruitment rate[18 week follow up];Data completeness[18 week follow up];Acceptability<br>This outcome will be assessed using a survey that will ask participants whether they found the intervention useful (yes/no), whether they recommend the intervention to others (yes/no), and whether they would continue with the exercises and the strategies they have been taught to manage their pain (yes/no).[18 week follow up]

Secondary Outcome Measures

Name	Time	Method
Daily analgesic dosage and type[Taken daily during the 18 week study period via a logbook];Beliefs on medication use (Beliefs about Medicines Questionnaire)[Baseline, 6 week (assessment #1) and 18 week (assessment #2) assessments];Views on exercise (Exercise Benefits/Barriers Scale)[Baseline, 6 week (assessment #1) and 18 week (assessment #2) assessments];Adverse events from the exercise (e.g. muscle strain)[Weekly during the study period, via the logbook];Knee related pain and physical function (Western Ontario and McMaster Universities Osteoarthritis Index)[Baseline, 6 week (assessment #1) and 18 week (assessment #2) assessments];Levels of physical activity (International Physical Activity Questionnaire, short form)[Baseline, 6 week (assessment #1) and 18 week (assessment #2) assessments];Physical activity levels using objective measures through activity monitors using a wrist-worn accelorometer. [Baseline, 6 week (assessment #1) and 18 week (assessment #2) assessments]