Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 33
- Locations
- 2
- Primary Endpoint
- Assessment of Chlorine ion production change
Study Overview
Brief Summary
Erythromelalgy (EM) is a vascular syndrome very rare affecting the feet. This disease evolve by crisis when the feet extremities become red hot and painful. There are several types of EM but this study concern the adult primitive form. For a long time, the physiopathology was not described but now we know that there is a vascular form, with microcirculatory dysfunction and a neurologic form with small fibers neuropathy. The diagnostic of neurologic form is based on clinical evaluation (DN4 questionnaire, UENS scale...) and an electromyography. Thermotest, a medical device which measure the thermic sensitivity is used to quantify neuropathy. More recently Sudoscan, a device measuring cutaneous impedance to chloride ions detect small nervous fiber in diabetic patients with good correlation with Thermotest.
The purpose of this study is to analyze the vascular side and the neurologic side on patients consulting for Erythromelalgy.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Pain with burn feeling at hands and feet extremities
- •Crisis activated by the heat
- •Age > 18 years old
Exclusion Criteria
- •Patients who had burn in extremities
Arms & Interventions
erythermalgia patient
patient will be measured chlorine ions impedance with the SUDOSCAN and evaluation on pain du to temperature with the THERMOTEST
Intervention: impedance measurement and pain evaluation (Other)
Outcomes
Primary Outcomes
Assessment of Chlorine ion production change
Time Frame: Day1
patient will be measured the impedance of chlorinates ions by Sudoscan
Assessment of Temperature changing sensitivity
Time Frame: Day1
Patients will be measured their sensitivity to temperature changing using the Thermotest
Secondary Outcomes
No secondary outcomes reported