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Examination of Potassium Levels in Saliva in ESRD Patients

Conditions
ESRD
Interventions
Procedure: sialometry
Procedure: blood test
Registration Number
NCT02596386
Lead Sponsor
Hadassah Medical Organization
Brief Summary

Dialysis patients typically undergo 3 treatments a week every other day with an almost 3 day gap during the weekend. After this gap and before the first dialysis of the week the serum Potassium level is expected to be maximal.

Participants will be recruited from the dialysis clinic at Hadassah Ein Kerem Hospital. The research team would personally meet the patients who answer inclusion criteria f and ask whether they wish to participate.

Each willing participant will undergo Sialometry and blood will be drawn from the dialysis connections for CBC and Biochemistry to establish a baseline.

The study measurements namely Sialometry and collection of Saliva as well as blood test will be taken before the initiation of the dialysis.

Blood testing will be done via the laboratories of the Hadassah hospital. Saliva analysis will be done in the research lab of Prof. Doron Aframian.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Present a predialysis serum potassium level over 5 mmol/L.
Exclusion Criteria
  • Pregnancy

Patients diagnosed with a pathology of the salivary glands such as Sjogren's syndrome, Sialosis, Sialadenitis.

Patients who have received previous radiation therapy to the head and neck region

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
potassium level in salivasialometryEach willing participant will undergo Sialometry
blood testblood testblood will be drawn from the dialysis connections for Biochemistry for potassium level evaluation
Primary Outcome Measures
NameTimeMethod
potassium level in saliva7 days
Standard Biochemistry of blood7 days
Secondary Outcome Measures
NameTimeMethod
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