to check the effect of gum treatment on the blood lipid levels of individuals having altered lipid levels

Not Applicable

Completed

• Conditions: Health Condition 1: null- chronic periodontital disease with hypercholesteromia

• Registration Number: CTRI/2016/03/006700
• Lead Sponsor: Jasmine Malhotra

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

The inclusion criteria consisted of patients having altered lipid profile i.e. the patients having hypercholesterolemia and falling under the moderate risk or low risk and those that can be treated by Therapeutic Lifestyle Changes (TLC) only (as given by American heart association ATP III guidelines. Patients should not be on any cholesterol lowering drugs and otherwise systemically healthy patients within the age group of 30-65 yrs. Patients with pocket probing depth >=5 mm with clinical attachment loss of >=1 mm (>=2quadrants). Presence of a minimum of 20 teeth was obligatory for inclusion in the clinical trial.

Exclusion Criteria

patients having history of any systemic disease like renal, hepatic, cardiac, diabetes, immunological or haematological disorders with contra-indication for minor oral surgical procedure, pregnant women, patients on chemotherapeutic agents in the previous 3 months or oral antiseptics in the previous month, previous periodontal treatment over the past six months, patients on estrogen replacement therapy and patients on folic acid or vitamin B6 or B12.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
decrease in clinical periodontal parameters and serum lipid profile parametersTimepoint: baseline and 3 months

Secondary Outcome Measures

Name	Time	Method
decrease in resistin, BMI and waist-hip ratioTimepoint: baseline and 3 months