Assessment of Blood Flow, Vascular Permeability and Oxygen Metabolism in Brain Tumors with Magnetic Resonance Imaging
Not Applicable
- Conditions
- ormal subjects and patients with brain tumors
- Registration Number
- JPRN-UMIN000015827
- Lead Sponsor
- Hokkaido University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1.Metallic implant or device not applicable to MRI 2.Unable to be at rest on his/her back or claustrophobia 3.Pregnant 4.Other inadequate cases 5.Allergic to gadlinium agents 6.Renal failure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Step 1-2 Correlation between StO2 values of lower extremity calculated by QSM and percutaneously measured by pulse oxymeter. Step 2 (1)Correlation between StO2 value calculated by QSM and 18F-FMISO accumulation (2)Comparison between distributions of hypoxic areas illustrated by QSM and FMISO-PET
- Secondary Outcome Measures
Name Time Method Step 1-2 Correration between StO2 value of lower extremity calculated by QSM and applied pressure Step 2 (1)Correlations between MRI findings in ASL/DCE and 18F-FMISO accumulation (2)Relation between results in radiation therapy and MR findings before radiation, change in MR findings between pre and post radiation (3)Relation between histopathology and MR findings in metastatic brain tumors