Prophylaxis of opioid induced pruritus in labor analgesia
Phase 2
- Conditions
- Intra echal Opioid Induced Pruritus.Other complications of spinal and epidural anaesthesia during labour and delivery
- Registration Number
- IRCT2016052328010N1
- Lead Sponsor
- Vice chancellor for Research and Technology, Hamadan University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 63
Inclusion Criteria
parturient aged 18-45 and ASA I with gestational age 36-42 weeks that candidates for labor under regional analgesia.
Exclusion criteria: preeclampsia; chronic hypertension; diabetes mellitus; allergy to drugs in the study; contraindication of neuraxial anesthesia; mother addiction and drug abuse and any unexpected accident that need for cesarean section; previous history of itching and allergy.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intratechal opioid induced pruritus. Timepoint: just after spinal anesthesia, 5, 10, 15 min later then every 15 mint to 90 min. Method of measurement: Pruritus was asses by observe the scraching and by Visual Analouge Scale of pruritus every 5 Minute for 15 minute and every 15 mnutes untile 90 min.
- Secondary Outcome Measures
Name Time Method Other complication of spinal anesthesia: nausea & vomitting, hypotension. Timepoint: After spinal anesthesia untile the end of labor or to 90 min after spinal anesthesia. Method of measurement: Blood pressure was measured with automatic blood pressure device and hypotension was defined as more than 20% decrease of BP compared to baseline, and observation of any retching or explosion Of gastric content.