Spontaneous breathing in general anesthesia using a closed-loop ventilation mode with a (semi-)automated weaning protocol
Not Applicable
- Conditions
- major vascular Surgery
- Registration Number
- DRKS00015786
- Lead Sponsor
- Kath. Klinikum Bochum gGmbH - St. Josefs-Hospital Klinik für Anästhesiologie und operative Intensivmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
all patients who receive general anaesthesia without muscle relaxation at the Catholic Clinic Bochum for surgery
- ASA 1-3
ASA
The Classification of the American Society of Anesthesiologists (ASA Classification I-VI) is a widely applied categorization of the preoperative status of patients. It has a good predictive value regarding perioperative morbidity and mortality.
Exclusion Criteria
-patients under 18 years of age
-patients older than 80 years
-lack of information or agreement
-Pregnancy
-Simultaneous participation in another study
-severe asthma/ COPD
-chronic pain syndrome with long-term opioid therapy
-intolerance to Sevoflurane (e.g. malignant hyperthermia or muscle disease) or opioids
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of spontaneous breathing in the OP time
- Secondary Outcome Measures
Name Time Method - Opioid consumption<br>- Wake-up and extubation time<br>- Operator satisfaction<br>- etCO2 in target range during controlled ventilation (etCO2 30-40mmHg)<br>- SpO2 in target range (SpO2 >94%)<br>- PEEP, ventilation pressure difference and ventilation peak pressure<br>- Dead space measurement (CO2- VT)<br>- Pain score in the recovery room<br>- Recovery room length of stay<br>- Anaesthesia depth measurement using EEG (Narcotrend)