Brain imaging study on the relation between emotion and cognitive functio
- Conditions
- Dementia Mild cognitive impairment
- Registration Number
- JPRN-UMIN000023038
- Lead Sponsor
- Preeminent Medical Photonics Education & Research Center, Hamamatsu University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Not provided
1. Individuals who have a history of traumatic brain injury with an unconsciousness lasting more than 5 minutes 2. Individuals who have a history of organic brain disease 3. Individuals who have a history of psychiatric disease 4. Individuals who have a history of substance dependence 5. Individuals who are taking central nervous system stimulants 6. Individuals who have a history of disorders of consciousness and/or seizure 7. Individuals who have a chronic headache 8. Individuals who have a risk for MRI scan 9. Criteria for elderly subject: 1) Individuals who have one or multiple following diagnosis: dementia (AD, FTLD, DLB), MCI, brain damage (cerebral infarction, brain hemorrhage, head trauma), Parkinsonism, Parkinson syndrome, corticobasal degeneration, 2) Individuals who have one or multiple following symptoms or disease: hearing difficulty, impaired vision, finger tremor, disease of cervical spine, cervical injury, neck pain
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Brain activations (BOLD signal changes, hemoglobin concentration changes) and brain chemistry concentrations, such as GABA and Glx levels
- Secondary Outcome Measures
Name Time Method Correlations between neuroimaging data (BOLD signal changes, hemoglobin concentration changes and brain chemical substances) and neuropsychological test scores