Hemostatic Profiling to Enable Personalized Antithrombotic Therapy in Patients after Pulmonary Embolism
Recruiting
- Conditions
- I26.0Pulmonary embolism with mention of acute cor pulmonale
- Registration Number
- DRKS00029668
- Lead Sponsor
- niklinik Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
age 18 years or older
Acute Pulmonary Embolism
Right ventricular dysfunction
Meeting criteria for intermediate risk Pulmonary embolism according to ESC Guidelines
Exclusion Criteria
Known significant bleeding risk
Administration of thrombolytic agents within the previous 4 days
Vena cava filter insertion or pulmonary thrombectomy within the previous 4 days
Previous enrolment in this study
Any other condition that the investigator feels would place the patient at increased risk if the investigational therapy is initiate
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method At the beginnen and 24-96h after treatment the ratio of the diameters of the right and left ventricle is assessed via echocardiografie. Primary outcome is the change of RV/LV ratio under therapy.
- Secondary Outcome Measures
Name Time Method In hospital mortality<br>Bleeding<br>Haemodynamic stability<br>Exploratory markers<br>Development of CTEPH<br>