Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or TE

The objectives of this PHRC are:

• the phenotypic analysis of the intestinal epithelial dysplasia by clinical and histo-pathological investigations.
• the identification of proteins involved at the intestinal level in the differentiation, the proliferation and the membership of the epithelial cells
• from the phenotypic study, a genetic analysis of type maps by homozygote on the whole genome partner in an approach guided by possible candidate genes
• the study of the genes, chosen according to their location, to their profile of expression, and to their function in touch with the pathogenic hypotheses