Examining Changes in Muscle Size and Body Composition Between Two Hypertrophy Resistance Training Programs in Males

Not Applicable

Completed

• Conditions: Hypertrophy; Body Weight Changes; Muscle Size
• Interventions: Other: Resistance Training Program

• Registration Number: NCT05667233
• Lead Sponsor: Dalhousie University

Brief Summary

This study aims to investigate if a less physically and psychologically taxing approach to resistance training can generate equal or greater outcomes when compared to a more physically and psychologically taxing approach.

Detailed Description

Resistance training is commonly used to improve body composition, gain strength, increase muscle size (i.e., hypertrophy) and prevent muscle atrophy (i.e., muscle wasting). The most optimal mode of building muscle remains unclear, however there are many mechanisms that can be tested to yield optimal results. One variable that can be manipulated when designing a hypertrophy-focused resistance training regimen is intensity (i.e., proximity-to-failure). Proximity-to-failure is defined as the number of repetitions remaining in a set of prescribed exercises prior to reaching momentary muscular failure (MMF). MMF is when an individual cannot complete the lowering or concentric phase of a given repetition with a full range-of-motion without deviation from the prescribed form of the exercise. For all lifters, particularly amongst older populations, it can be psychologically demanding to push to MMF, and may increase the risk of delayed onset muscle soreness (DOMS) and/or injury due to technical breakdown. In contrast, there is some evidence that suggests training to a slightly less intensity (i.e., within 1-4 repetitions in reserve \[RIR\]) may result in comparable hypertrophic results with less of a physical and psychological demand on participants.

For these reasons, this study looks to investigate if an easier (i.e., less intense) approach to training such as training with repetitions in reserve (RIR), warrants similar or better muscle hypertrophy adaptations to MMF.

Study Timeline

• Study First Submitted: 2022-12-19
• Study First Submitted QC: 2022-12-19
• Study First Posted: 2022-12-28
• Study Start: 2023-02-06
• Primary Completion: 2023-03-27
• Study Completion: 2023-04-03
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-11
• Last Update Posted: 2023-08-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 13

Inclusion Criteria

• biological male
• age 18 years or older
• enrolled at Dalhousie university
• minimum 3-months of consistent (at least 2x/week) resistance training experience

Exclusion Criteria

• body fat percentage 25% or greater (obese)
• use of performance enhancing drugs that aim to increase rate of muscle growth (i.e., androgenic steroids, anabolic steroids, selective androgen receptive modulators, growth hormone).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Train to non-failure	Resistance Training Program	Training regime will be moderately uncomfortable as participants will be training at a close proximity to failure (4-0 repetitions in reserve; i.e., non-failure).
Train to failure	Resistance Training Program	Training regime will be highly uncomfortable since it will be both physically and psychologically challenging to push to momentary muscular fatigue (MMF; i.e., failure).

Primary Outcome Measures

Name	Time	Method
Segment girth (cm)	8-weeks	Upper arm (biceps) circumference, mid-thigh (quadriceps) circumference, waist (abdomen) circumference

Secondary Outcome Measures

Name	Time	Method
Body composition (kg)	8-weeks	Fat mass, Fat-free mass, Total Body Mass (fat mass + fat free mass)
Body Fat Percentage	8-weeks	Fat Mass (kg) / Total Body mass (kg) \* 100

Trial Locations

Locations (1)

Dalplex Fitness Centre; 🇨🇦 Halifax, Nova Scotia, Canada