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Clinical Trials/NCT01316471
NCT01316471
Completed
Phase 2

Web-MAP 2: Internet Intervention for Adolescents With Chronic Pain

Seattle Children's Hospital1 site in 1 country273 target enrollmentMay 2011

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Chronic Pain
Sponsor
Seattle Children's Hospital
Enrollment
273
Locations
1
Primary Endpoint
Pain intensity
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the efficacy of a web-based (i.e., internet) behavioral program to reduce pain and improve functioning in children and adolescents with chronic pain. We hypothesize that children and adolescents in families that receive the web-based behavioral program will report reduced pain levels and improved daily functioning compared to children and their parents who receive online patient education.

Detailed Description

An estimated 15% to 30% of otherwise healthy children and adolescents suffer from recurrent or chronic pain such as headache, abdominal pain, and musculoskeletal pain. Chronic pain has a significant impact on children's mood, daily functioning, and overall quality of life. Effective behavioral interventions have been developed to increase positive coping behaviors. However, most children do not have access to these interventions due to a variety of barriers such as distance from pediatric pain treatment centers. We have developed an online behavioral intervention called Web-based Management of Adolescent Pain (Web-MAP), and our preliminary findings indicated that children in families that received this intervention experienced significant improvements in their pain level and daily functioning compared to children who did not receive the intervention (Palermo et al., 2009). The purpose of this study is to extend these findings by: 1) recruiting families from other medical centers, 2) determining whether the benefits of online behavioral intervention are maintained 6- and 12-months after the intervention has been completed, 3) evaluating additional outcomes such as parent responses to pain and child sleep quality, anxiety, depression, and health service use, 4) comparing results from online behavioral intervention to online patient education.

Registry
clinicaltrials.gov
Start Date
May 2011
End Date
November 2015
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Tonya Palermo

Professor, Anesthesiology and Pain Medicine

Seattle Children's Hospital

Eligibility Criteria

Inclusion Criteria

  • Literate in English
  • Age 11-17 years
  • Pain present for at least 3 months duration
  • Pain occurs at least 1 time per week and interferes with daily functioning
  • Pain is not related to a chronic disease
  • Receiving evaluation or treatment in a pediatric pain clinic
  • Has access to a computer, the Internet, and a phone

Exclusion Criteria

  • A serious comorbid chronic condition in the patient (e.g., diabetes, arthritis, cancer).
  • Non-English speaking
  • More than 4 sessions of CBT for pain management in the 6 months prior to the time of screening.

Outcomes

Primary Outcomes

Pain intensity

Time Frame: pre-treatment, immediately post-treatment, 6-month follow-up, 12-month follow-up

Children will report on presence and intensity of pain daily for 7 days at each assessment period. Pain intensity will be assessed using an 11-point numerical rating scale (NRS) with anchors of 0= no pain to 10= worst pain (McGrath et al., 2008). Mean average intensity of the pain reported will serve as primary pain measure.

Activity limitations

Time Frame: pre-treatment, immediately post-treatment, 6-month follow-up, 12-month follow-up

Child report of activity limitations will be assessed using the prospective version of the Child Activity Limitations Interview (Palermo, Witherspoon, Valenzuela, \& Drotar, 2004), which includes 8 activities that children identify as important in their day-to-day lives that are impacted by pain. Responses are rated on a 5-point scale (0-4) with higher scores indicating greater perceived difficulty with activities. Children will provide ratings daily for 7 days on their online diaries at each assessment period. Mean activity limitations across the reporting period is used in analyses.

Secondary Outcomes

  • Sleep Quality(pre-treatment, immediately post-treatment, 6-month follow-up, 12-month follow-up)
  • Depression and pain-specific anxiety(pre-treatment, immediately post-treatment, 6-month follow-up, 12-month follow-up)
  • Treatment Satisfaction(Immediately Post-Treatment, 6-month follow-up, 12-month follow-up)
  • Parental Response to Pain Behavior(pre-treatment, immediately post-treatment, 6-month follow-up, 12-month follow-up)
  • Health service Use(pre-treatment, 12-month follow-up)
  • Miscarried Helping(pre-treatment, immediately post-treatment, 6-month follow-up, 12-month follow-up)

Study Sites (1)

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