Quantitative cell free DNA from spent culture media at 48 and 54hours after Cleavage stage of embryo

Phase 1

Completed

• Conditions: Infertility couple with indication for preimplantation genetic testing; preimplantation genetic testing; noninvasive; spent culture media

• Registration Number: TCTR20210209003
• Lead Sponsor: Faculty of Medicine Ramathibodi hospital Mahidol university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-01-31
• Study Start: 2021-02-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 52

Inclusion Criteria

Female age between 30-45years old
Infertility
Indicated for PGT-A

Exclusion Criteria

Embryonic culture less than day 5
Embryonic grading less than early blastocyst stage (reference from Gardner and schoolcraft morphology classification,1999)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
DNA quantity 12 months qPCR, Qubit

Secondary Outcome Measures

Name	Time	Method
Concordance of chromosome study result by spent culture media compare with trophectoderm biopsy 12 months trophectoderm biopsy