The effect of different antibiotic protocols for dental implant surgery on peri-implant tissue health and on oral microbiome and resistome
- Conditions
- healthy patientsTherapeutic area: Diseases [C] - Stomatognathic Diseases [C07]
- Registration Number
- CTIS2023-510391-31-00
- Lead Sponsor
- niversita Degli Studi Di Genova
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 80
Patients requiring one single implant or partial implant-supported rehabilitation in an edentulous area of the posterior mandible or maxilla
- Patients unable to commit to follow-up - General contraindications to implant surgery - Immuno-suppressed/immune-compromised patients - Patients irradiated in the head and/or neck - Uncontrolled diabetes - Pregnancy, childbearing potential, breastfeeding - Smoking habit - Untreated periodontal disease (Caton et al, J Clin Periodontol 2018) - Poor oral hygiene and motivation (plaque index > 20%) - Addiction to alcohol or drugs - Psychiatric problems and/or unrealistic expectations - Patients with an acute infection (abscess) or suppuration in the site intended for implant placement - Patients treated or under treatment with intravenous amino-bisphosphonates - Patients referred only for implant placement if the follow-up cannot be done at the treatment center - Patients participating in other studies, if the present protocol could not be fully adhered to - Patients with allergy/hypersensitivity to penicillin or drug excipients - Patients recently treated with antibiotics for other indications
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method