General Anesthesia exposure and neurodevelopmental outcome in Pediatric
Recruiting
- Conditions
- Surgeries related to dDuodenal-jejunal-ileal atresia repairs, anorectal malformation, Hirschsprung disease and/or inguinal hernia
- Registration Number
- NL-OMON26844
- Lead Sponsor
- Emma Children’s Hospital, Amsterdam UMC.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
In order to be eligible to participate in this study, a subject must meet all of the following criteria: age 12 months (± four weeks) with a history of general anesthesia exposure (patient group) or without a history of general anesthesia (healthy controls)
Exclusion Criteria
Children with comorbid conditions affecting structure and/or function of the central nervous system (e.g. premature birth) will be excluded from participation in this study.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eurocognitive development as measured using eye-tracking metrics
- Secondary Outcome Measures
Name Time Method a.Conventional measures of neurocognitive development (Ages & Stages Questionnaire and Bayley Scales of Infant Development )<br>b.Total anesthesia time. Surgery and anesthesia time will be recorded by the (fellow) surgeon performing the operation(s). When multiple procedures are carried out, durations will be combined and these results will be retrieved during analysis of the data. <br>