NL-OMON29980尚未招募2 期
Preoperative short-term radiotherapy for primary resectable rectal cancer: Accelerated once daily (5x5Gy) versus accelerated hyperfractionated twice daily (12x2,5Gy b.i.d.) (ONCE-TWICE trial) A phase II single-blinded multi-institutional randomised study - ONCE-TWICE trial
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 210
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Primary resectable rectal cancer. All patients with primary resectable rectal cancer are eligible for the study, regardless whether a low anterior resection with primary anastomosis or an abdominoperineal resection is planned.
- •- Histologically proven adenocarcinoma
- •- No distant metastases
- •- No prior radiotherapy to the pelvis or abdomen
- •- Age >18 years
- •- WHO performance score 0-2
- •- Patients at reproductive age must agree to practice an effective contraceptive method
- •- Written informed consent
排除标准
- •- Non-resectable rectal cancer (or resectability uncertain)
- •- Histology other than adenocarcinoma
- •- Distant metastases
- •- Pregnancy or lactation
- •- Psychological, familial, sociological or geographical reasons hampering compliance with the study protocol and follow-up schedule; those conditions should be discussed with the patient before registration in the trial
研究者
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