Remimazolam during induction of anesthesia in patients with severe aortic stenosis
Not Applicable
- Conditions
- Severe aortic stenosis
- Registration Number
- JPRN-UMIN000042318
- Lead Sponsor
- agoya City University Graduate School of Medical Sciences, Department of Anesthesiology and Intensive Care Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients undergoing emergency surgery (2) Patients who are allergic to the study drugs (fentanyl, remifentanil, rocuronium, sugammadex, benzodiazepines, sevoflurane, desflurane) (3) Patients for whom the use of remimazolam is contraindicated (patients with acute angle-closure glaucoma, myasthenia gravis, shock, coma, and acute alcoholism with suppressed vital signs) (4) Patients with preoperative disturbance of consciousness (5) Patients who have been sedated preoperatively (6) Patients deemed inappropriate by the principal investigator/associators (excluded with reasons for exclusion)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dosage of vasoconstrictor and inotropic agents during induction of anesthesia.
- Secondary Outcome Measures
Name Time Method Hemodynamic change (blood pressure and heart rate). Time to loss of consciousness, time from the start of anesthesia induction to the end of tracheal intubation, total remimazolam dose, change in BIS (bispectral index) level, change in TOI (tissue oxygenation index), postoperative nausea and vomiting, incidence of postoperative delirium, presence or absence of awareness at the time of induction of anesthesia, and postoperative flumazenil use and dose.