CO2 Laser and Open Surgery for T1N0 Glottic SCC With Anterior Commissure Involved

Not Applicable

• Conditions: Squamous Cell Carcinoma of Glottis

• Registration Number: NCT02303457
• Lead Sponsor: Xuekui Liu

Brief Summary

Open surgery and CO2 laser surgery are both established treatment modalities for T1N0 glottic carcinoma. It is controversial for T1N0 glottic carcinoma with anterior commissure involved.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07
• Study First Submitted: 2014-11-02
• Study First Submitted QC: 2014-11-28
• Study First Posted: 2014-12-01
• Status Verified: 2016-01
• Last Update Submitted: 2016-01-27
• Last Update Posted: 2016-01-28
• Primary Completion: 2024-07
• Study Completion: 2024-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 402

Inclusion Criteria

• T1N0 SCC of glottic carcinoma with anterior commissure involve
• No nodal metastasis and distant metastasis
• All patients must have CT/MR and electronic laryngoscope test before surgery and after surgery
• Expected lifetime>1 year
• Patients and families agreed to participate in the test and sign the informed consent
• Without cognitive impairment.

Exclusion Criteria

• With severe cardiac insufficiency Liver and kidney function is not complete systemic infection patients
• Patients with pregnancy and lactation
• Have surgery contraindications

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Primary Outcome Measures

Name	Time	Method
disease-free survival	5 years

Secondary Outcome Measures

Name	Time	Method
recurrence rate	5 years

Trial Locations

Locations (1)

Sun Yat-sen University Cancer Center; 🇨🇳 Guangzhou, Guangdong, China