ITMCTR2024000094Not yet recruitingPhase 1
Study on the mechanism of Jiawei Bushen Zhuangjin Decoction in treating knee osteoarthritis based on transcriptomics
Henan University of Chinese Medicine0 sitesStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 1
- Status
- Not yet recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 50 to 70 (—)
- Sex
- All
Inclusion Criteria
- •1) Patients who meet the diagnostic criteria for KOA (unilateral or bilateral);
- •2) Patients aged between 50 and 70 years old, both male and female;
- •3) The X-ray K-L grade of the knee joint belongs to grade II-III;
- •4) KOA stage belongs to the early and middle stages;
- •5) Patients with good basic conditions, suitable for drug treatment, and no obvious indications of surgery;
- •6) The patient had good compliance and signed the informed consent.
Exclusion Criteria
- •1) Have taken traditional Chinese medicine decoction, proprietary Chinese medicine or other Western medicine with KOA treatment in the past week;
- •2) Participants in other research projects before enrollment;
- •3) Patients with knee joint tumor, tuberculosis, rheumatism, rheumatoid arthritis, gouty arthritis and other diseases;
- •4) Patients who have undergone knee replacement;
- •5) Pregnant or planning to become pregnant or lactating women;
- •6) Patients with severe primary diseases of the heart, cerebrovascular and hematopoietic systems, mental diseases, malignant tumors, and liver and kidney dysfunction;
- •7) Participants in other clinical trials that affect the evaluation of the results of this study.
Investigators
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