Effects of Botulinium Toxin-A in perennial allergic rhinitis patients resistant to conventional treatments
Not Applicable
- Conditions
- perennial allergic rhinitis.other allergic rhinitis/perennial allergic rhinitis
- Registration Number
- IRCT201206079963N1
- Lead Sponsor
- niversity of Social Welfare and Rehabilitation sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Males and females age between 20-40; Having perennial (minimum of three years) allergic rhinitis who have received conventional treatments with no results; Having a minimum educational level ( high school diploma); Being stable in emotional,physical and other health status suitable for entering study ; Informed consent to be understood and be signed voluntarily.
Exclusion criteria:
Ages below 20 or above 40 years; History of chronic sinusitis,asthma and or other systemic disoredrs ; History of using Botulinium Toxin type -A for any reason; Rejecting to accept and or signing the informed consent.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relieving symptoms of perennial allergic rhinitis such as itching(eyes,ears and nose),sneez and rhinorrhea after intervention. Timepoint: 1,3,6 and 12 weeks post intervention. Method of measurement: smyptoms chart converting qualitative symptoms of itching(eyes,ears,nose),sneez and rhinorrhea to quantitative from no symptoms(0) to worst symptoms(10) .Scorings are collected in both groups for final statistical analysis.
- Secondary Outcome Measures
Name Time Method Observing any drug`s side effects in intervetion group. Timepoint: 1,3,6 and 12 weeks post intervention. Method of measurement: Recording any kinds of side effects in pre-designed chart related to each patient from degrees of not having (0) to sever degrees of side effects (10).