fMRI investigation of the neural mechanisms of Emotional Cognitive Bias Modification as an adjunct therapy to SSRIs in depression.

niversity of Bristol0 sites84 target enrollmentNovember 12, 2020

Overview

No summary available.

Registry

who.int

Start Date

November 12, 2020

End Date

July 31, 2024

Last Updated

last year

Study Type

Interventional

Sex

All

Sponsor

niversity of Bristol

•Current inclusion criteria as of 01/12/2022:
•1\. Aged 18 \- 55 years
•2\. Have a new or first episode of depression (defined as not prescribed an antidepressant in the previous 6 months)
•3\. Prescribed a course of SSRI medication
•4\. Score \>10 on the PHQ\-9 assessment
•Previous inclusion criteria:
•1\. Aged 18 \- 55 years
•2\. Have a new or first episode of depression (defined as not prescribed an antidepressant in the previous 6 months)
•3\. Prescribed a course of sertraline medication
•4\. Score \>10 on the PHQ\-9 assessment

•Current exclusion criteria as of 01/12/2022:
•1\. Prescribed an antidepressant in the previous 6 months
•2\. Had a course of high intensity psychological treatment in the last 6 months
•3\. Alcohol or substance dependency
•4\. Bipolar disorder, Schizophrenia/Psychosis
•5\. Dementia
•6\. Currently under psychiatric care (including those referred but not yet seen) for depression
•7\. Unable to access online CBM sessions (PC, laptop, phone)
•8\. Cannot complete questionnaires unaided or would require an interpreter
•9\. Are taking part in another trial involving a psychological/drug intervention