ERECTOR SPINAE PLANE BLOCK COMBINED WITH GENERAL ANAESTHESIA VERSUS CONVENTIONAL GENERAL ANAESTHESIA IN LUMBAR SPINE SURGERY
Overview
- Phase
- Not Applicable
- Intervention
- Erector spinae plane block
- Conditions
- Anaesthetic Drugs, Hypotensive Drugs, Perioperative Analgesia
- Sponsor
- Mohamed Elsayed
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Anaesthetic requirements:
- Last Updated
- 6 years ago
Overview
Brief Summary
Ultrasound guided erector spinae plain block combined with general anaesthesia versus conventional general anaesthesia in lumbar spine surgery, it's hypothesized that combined regional anaesthesia with general anaesthesia in lumbar spine surgery may reduce the anaesthetic requirements, aid in controlled hypotension and improve the perioperative pain management.
Detailed Description
Primary outcomes: • Anaesthetic requirements: based on entropy monitoring(state and response entropy monitoring and the difference as a measure for adequacy of analgesia) and haemodynamic parameters ( heart rate and mean arterial blood pressure) at the following time intervals: before induction, after induction, after giving either ESP block or multimodal analgesia and starting surgical stimulus, at 30 min intervals, at end of anaesthesia, at eye opening. Secondary outcomes: * Stress response measurement based on serum cortisol and blood glucose levels * Controlled hypotensive anaesthesia: various drugs required and doses given * Intraoperative and postoperative analgesia. * Postanaesthesia care unit data concerning recovery.
Investigators
Mohamed Elsayed
doctor
University of Alexandria
Eligibility Criteria
Inclusion Criteria
- •patients undergoing lumbar spine surgery
Exclusion Criteria
- •Coagulation disorders.
- •BMI \> 30 or \< 18.
- •Patients with surgical site infection.
- •Patients with unstable spine integrity like fractures or scoliosis.
- •Hypertensive ,cardiac and diabetic patients.
Arms & Interventions
ultrasound guided erector spinae block and general anaesthesia
Ultrasound guided erector spine plane block is done after general anaesthesia and prone positioning
Intervention: Erector spinae plane block
Multimodal analgesia with general anaesthesia
Multimodal analgesia given with general anaesthesia in form of ketorolac and paracetamol
Intervention: Multimodal analgesia
Outcomes
Primary Outcomes
Anaesthetic requirements:
Time Frame: the surgery period
based on entropy monitoring and haemodynamic parameters.